Core-Own A™ “28“ Herbal Adaptogenic Enhancer The physical core of the human body is its skeleton, the core of the bones their marrow, producing and housing progenitor cells of the body’s immune system. When we own our core, we unite with ourselves, mind with body, immunologically competent, lympho-neurically tuned.

Core-Own A™ “28” combines extracts of twenty-eight natural or, whenever possible, certified organically grown, herbs to help the individual “own his / her core,” to be in tune with one's immunological self as well as one’s psychological self. The formula is led by the flowers of the pomegranate tree, Punica granatum Flos, and followed by the peels of the tree’s fruit, Punica granatum Pericarp, and twenty-six additional herbs including one medicinal mushroom, as listed below. A brief notation on each herb, including references, follows the list. 1. 100 Punica granatum Flos
2. 100 Punica granatum Pericarp
3. 1000 Zingiber officinale Rhizome (fresh)
4. 1000 Astragalus membranaceus Radix
5. 1000 Pueraria montana Radix
6. 15 Ceanothus americanus Radix
7. 1000 Scutellaria baicalensis Radix
8. 15 Lonicera japonica Flos
9. 300 Atractylodes macrocephala Radix
10. 50 Cinnamomum cassia Cortex
11. 30 Acorus calamus Rhizome
12. 90 Panax ginseng Radix
13. 200 Citrus reticulata Pericarp
14. 5 Peganum harmala Semen 15. 9 Cordyceps militaris Sporocarp
16. 100 Humulus lupulus Flos
17, 100 Ginkgo biloba Folium
18. 50 Urtica dioica Folium
19. 20 Hypericum perforatum Folium
20. 10 Olea europaea Folium
21. 30 Schisandra chinensis Fructus
22. 80 Musa acuminata Pericarp
23. 40 Oldenlandia diffusa
24. 100 Eriobotrya japonica
25. 10 Tripterygium wilfordii Cortex Radix
26. 20 Commiphora myrrha Resina
27. 80 Glycyrrhiza glabra Radix
28. 10 Curcuma longae Rhizoma
29. 100 Angelica sinensis Radix Core-Own A™ Herbal Adaptogenic Enhancer Punica granatum Flos These are the beautiful flowers of the pomegranate tree, rich in ursolic acid and related pentacyclic triterpenoids, dietary compounds with great healing power.

Howell AB, D'Souza DH. The pomegranate: effects on bacteria and viruses that influence human health. Evid Based Complement Alternat Med. 2013;2013:606212.

Katz SR, Newman RA, Lansky EP. Punica granatum: heuristic treatment for diabetes mellitus. J Med Food. 2007;10(2):213–217.

Sharifiyan F, Mirjalili SA, Fazilati M, Poorazizi E, Habibollahi S. Variation of ursolic acid content in flowers of ten Iranian pomegranate (Punica granatum L.) cultivars. BMC Chem. 2019;13(1):80.

Tohmé MJ, Giménez MC, Peralta A, Colombo MI, Delgui LR. Ursolic acid: A novel antiviral compound inhibiting rotavirus infection in vitro. Int J Antimicrob Agents. 2019;54(5):601–609.
 Core-Own A™ Herbal Adaptogenic Enhancer Punica granatum Pericarp The antiviral activity of pomegranate fruit peel extracts was early recognized for its potential in the treatment of acquired immunodeficiency syndrome and was the subject of a patent promoting its antiviral actions acquired by pharmaceutical giant Merck.

Houston DMJ, Bugert JJ, Denyer SP, Heard CM. Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV [published correction appears in PLoS One. 2017;12(11):e0188609]. PLoS One. 2017;12(6):e0179291.

Moradi MT, Karimi A, Shahrani M, Hashemi L, Ghaffari-Goosheh MS. Anti-Influenza Virus Activity and Phenolic Content of Pomegranate (Punica granatum L.) Peel Extract and Fractions. Avicenna J Med Biotechnol. 2019;11(4):285–291.
 Core-Own A™ Herbal Adaptogenic Enhancer Zingiber officinale Rhizome (fresh) Ginger rhizome, in its fresh form, is possibly the most universally beloved herb.

Chakraborty B, Sengupta M. Boosting of nonspecific host response by aromatic spices turmeric and ginger in immunocompromised mice. Cell Immunol. 2012;280(1):92–100.

Chang JS, Wang KC, Yeh CF, Shieh DE, Chiang LC. Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. J Ethnopharmacol. 2013;145(1):146–151.

Rasool A, Khan MU, Ali MA, et al. Anti-avian influenza virus H9N2 activity of aqueous extracts of Zingiber officinalis (Ginger) and Allium sativum (Garlic) in chick embryos. Pak J Pharm Sci. 2017;30(4):1341–1344.
 Core-Own A™ Herbal Adaptogenic Enhancer Astragalus membranaceus Radix The queen of external qi, astragalus, used intelligently with caution, bolsters immunity.

Khan HM, Raza SM, Anjum AA, Ali MA. Antiviral, embryo toxic and cytotoxic activities of Astragalus membranaceus root extracts. Pak J Pharm Sci. 2019;32(1):137–142.

Qi Y, Gao F, Hou L, Wan C. Anti-Inflammatory and Immunostimulatory Activities of Astragalosides. Am J Chin Med. 2017;45(6):1157–1167.

Zhang P, Liu X, Liu H, et al. Astragalus polysaccharides inhibit avian infectious bronchitis virus infection by regulating viral replication. Microb Pathog. 2018;114:124–128. Core-Own A™ Herbal Adaptogenic Enhancer Pueraria montana Radix The chalky white Japanese arrow-root is the common dietary kudzu,

Han P, Li J, Li WJ, Yu ZL, Wang Q, Wu DS. [Potential antiviral drug Pueraria crude extract and puerarin protect against ethanol-induced cytotoxicity in embryonic mouse hippocampal cultures]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2005;19(3):244-7.

Lin TJ, Yeh CF, Wang KC, Chiang LC, Tsai JJ, Chang JS. Water extract of Pueraria lobata Ohwi has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. Kaohsiung J Med Sci. 2013;29(12):651–657.

Mediouni S, Jablonski JA, Tsuda S, et al. Potent suppression of HIV-1 cell attachment by Kudzu root extract. Retrovirology. 2018;15(1):64. Core-Own A™ Herbal Adaptogenic Enhancer Ceanothus americanus Radix New Jersey tea, aka red root, is a powerful, multipurpose, native American medicine.

Baltina LA, Flekhter OB, Nigmatullina LR, et al. Lupane triterpenes and derivatives with antiviral activity. Bioorg Med Chem Lett. 2003;13(20):3549–3552.
Buhner SH. Herbal Antivirals: Natural Remedies for Emerging & Resistant Viral Infections. North Adams, MA, USA: Storey Publishing, pp 416, pp 257-9.
Klein FK, Rapoport H. Ceanothus alkaloids. Americine. J Am Chem Soc. 1968; 90(9):2398-2404. Core-Own A™ Herbal Adaptogenic Enhancer Scutellaria baicalensis Radix For millennia, the root of this skullcap has reigned as a cardinal Chinese medicinal herb.

Ji S, Li R, Wang Q, et al. Anti-H1N1 virus, cytotoxic and Nrf2 activation activities of chemical constituents from Scutellaria baicalensis. J Ethnopharmacol. 2015;176:475–484.

Seong RK, Kim JA, Shin OS. Wogonin, a flavonoid isolated from Scutellaria baicalensis, has anti-viral activities against influenza infection via modulation of AMPK pathways. Acta Virol. 2018;62(1):78–85.

Zhi HJ, Zhu HY, Zhang YY, Lu Y, Li H, Chen DF. In vivo effect of quantified flavonoids-enriched extract of Scutellaria baicalensis root on acute lung injury induced by influenza A virus. Phytomedicine. 2019;57:105–116. Core-Own A™ Herbal Adaptogenic Enhancer Lonicera japonica Flos The Chinese prize unopened buds of honeysuckle to remedy cold and flu.

Mi HJ, Wang YX, Meng J, Wang XH, Tao YH, Wang ZZ. [Preliminary Analysis on Spectrum-Efficient Correlation Model for Anti-Influenza Virus of Lonicerae Japonicae Flos by Partial Least Squares Method]. Zhongguo Zhong Yao Za Zhi. 2015;40(23):4650–4654.

Yu Y, Zhu C, Wang S, Song W, Yang Y, Shi J. Homosecoiridoid alkaloids with amino acid units from the flower buds of Lonicera japonica. J Nat Prod. 2013;76(12):2226–2233.

Zhou W, Yin A, Shan J, Wang S, Cai B, Di L. Study on the Rationality for Antiviral Activity of Flos Lonicerae Japonicae-Fructus Forsythiae Herb Chito-Oligosaccharide via Integral Pharmacokinetics. Molecules. 2017;22(4):654. Core-Own A™ Herbal Adaptogenic Enhancer Atractylodes macrocephala Radix Bai zhu rhizome is a safe, nourishing, ancient Chinese medicinal tonic.

Cheng Y, Mai JY, Hou TL, Ping J, Chen JJ. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016;14(4):3704–3710.

Gu S, Li L, Huang H, Wang B, Zhang T. Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods. Molecules. 2019;24(16):2956. Published 2019 Aug 15.

Luo H, Tang QL, Shang YX, et al. Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs [published online ahead of print, 2020 Feb 17]. Chin J Integr Med. 2020;10.1007/s11655-020-3192-6. Core-Own A™ Herbal Adaptogenic Enhancer Cinnamomum cassia Cortex Cinnamon tree bark is delicious, warming, highly medicinal, and sacred.

Fatima M, Zaidi NU, Amraiz D, Afzal F. In Vitro Antiviral Activity of Cinnamomum cassia and Its Nanoparticles Against H7N3 Influenza A Virus. J Microbiol Biotechnol. 2016;26(1):151–159.

Fauvelle C, Lambotin M, Heydmann L, et al. A cinnamon-derived procyanidin type A compound inhibits hepatitis C virus cell entry. Hepatol Int. 2017;11(5):440–445.

Hayashi K, Imanishi N, Kashiwayama Y, et al. Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo. Antiviral Res. 2007;74(1):1–8. doi:10.1016/j.antiviral.2007.01.003

Yeh CF, Chang JS, Wang KC, Shieh DE, Chiang LC. Water extract of Cinnamomum cassia Blume inhibited human respiratory syncytial virus by preventing viral attachment, internalization, and syncytium formation. J Ethnopharmacol. 2013;147(2):321–326. Core-Own A™ Herbal Adaptogenic Enhancer Acorus calamus Rhizome Highly aromatic, sweet flag is a pillar of perfumery and Ayurveda, known to traditional Chinese medicine, the Native American, and the ancient Levant.

Rosmalena R, Elya B, Dewi BE, et al. The Antiviral Effect of Indonesian Medicinal Plant Extracts Against Dengue Virus In Vitro and In Silico. Pathogens. 2019;8(2):85.

Yao X, Ling Y, Guo S, et al. Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections. Phytomedicine. 2018;42:258–267.

Yao X, Ling Y, Guo S, et al. Inhibition of dengue viral infection by diasarone-I is associated with 2'O methyltransferase of NS5. Eur J Pharmacol. 2018;821:11–20. Core-Own A™ Herbal Adaptogenic Enhancer Panax ginseng Radix The king of yang tonics, ginseng is a powerful, pleiotropic adaptogen.

Lee JS, Cho MK, Hwang HS, et al. Ginseng diminishes lung disease in mice immunized with formalin-inactivated respiratory syncytial virus after challenge by modulating host immune responses. J Interferon Cytokine Res. 2014;34(11):902–914.

Lee JS, Ko EJ, Hwang HS, et al. Antiviral activity of ginseng extract against respiratory syncytial virus infection. Int J Mol Med. 2014;34(1):183–190.

Yoo DG, Kim MC, Park MK, et al. Protective effect of Korean red ginseng extract on the infections by H1N1 and H3N2 influenza viruses in mice. J Med Food. 2012;15(10):855–862.
Core-Own A™ Herbal Adaptogenic Enhancer Citrus reticulata Pericarp Dried tangerine peel lightens the effect and taste of strong tonic roots.

Sharikadze N, Jojua N, Sepashvili M, Zhuravliova E, Mikeladze DG. Mitochondrial Target of Nobiletin's Action. Nat Prod Commun. 2016;11(12):1833–1838.

Tang K, He S, Zhang X, et al. Tangeretin, an extract from Citrus peels, blocks cellular entry of arenaviruses that cause viral hemorrhagic fever. Antiviral Res. 2018;160:87–93.

Xu JJ, Wu X, Li MM, et al. Antiviral activity of polymethoxylated flavones from "Guangchenpi", the edible and medicinal pericarps of citrus reticulata 'Chachi'. J Agric Food Chem. 2014;62(10):2182–2189. Core-Own A™ Herbal Adaptogenic Enhancer Peganum harmala Semen The seeds of Persian esphand are powerful medicine, valuable even in tiny doses.

Benzekri R, Bouslama L, Papetti A, Hammami M, Smaoui A, Limam F. Anti HSV-2 activity of Peganum harmala (L.) and isolation of the active compound. Microb Pathog. 2018;114:291–298.

Chen D, Tian X, Zou X, et al. Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF-κB pathway. Int Immunopharmacol. 2018;60:111–120.

Lansky ES, Lansky S, Paavilainen, HM. Harmal: The Genus Peganum. Boca Raton, FL, USA: CRC Press, 277 pp.

Moradi MT, Karimi A, Rafieian-Kopaei M, Fotouhi F. In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus. Microb Pathog. 2017;110:42–49. Core-Own A™ Herbal Adaptogenic Enhancer Cordyceps militaris Sporocarp This unusual and most potent medicinal fungus grows from the carcass of a worm.
Lee HH, Park H, Sung GH, et al. Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA/2 mouse model. J Microbiol. 2014;52(8):696–701.

Ohta Y, Lee JB, Hayashi K, Fujita A, Park DK, Hayashi T. In vivo anti-influenza virus activity of an immunomodulatory acidic polysaccharide isolated from Cordyceps militaris grown on germinated soybeans. J Agric Food Chem. 2007;55(25):10194–10199.

Ueda Y, Mori K, Satoh S, Dansako H, Ikeda M, Kato N. Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris. Biochem Biophys Res Commun. 2014;447(2):341–345. Core-Own A™ Herbal Adaptogenic Enhancer Humulus lupulus Flos Hops, cousin of Cannabis in the Cannabaceae family, is the soporific bitter of beer.

Buckwold VE, Wilson RJ, Nalca A, et al. Antiviral activity of hop constituents against a series of DNA and RNA viruses. Antiviral Res. 2004;61(1):57–62.

Di Sotto A, Checconi P, Celestino I, et al. Antiviral and Antioxidant Activity of a Hydroalcoholic Extract from Humulus lupulus L. Oxid Med Cell Longev. 2018;2018:5919237. Published 2018 Jul 24.

Liu X, Bai J, Jiang C, et al. Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses. Vet Microbiol. 2019;238:108431.

Wang Q, Ding ZH, Liu JK, Zheng YT. Xanthohumol, a novel anti-HIV-1 agent purified from Hops Humulus lupulus. Antiviral Res. 2004;64(3):189–194.

Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015;103:71–82. Core-Own A™ Herbal Adaptogenic Enhancer Gingko biloba Folium Gingko is the world’s oldest living tree, over 3 and half million years young !

Haruyama T, Nagata K. Anti-influenza virus activity of Ginkgo biloba leaf extracts. J Nat Med. 2013;67(3):636–642.

Sochocka M, Sobczyński M, Ochnik M, Zwolińska K, Leszek J. Hampering Herpesviruses HHV-1 and HHV-2 Infection by Extract of Ginkgo biloba (EGb) and Its Phytochemical Constituents. Front Microbiol. 2019;10:2367.

Wang CZ, Li WJ, Tao R, Ye JZ, Zhang HY. Antiviral activity of a nanoemulsion of polyprenols from ginkgo leaves against influenza A H3N2 and hepatitis B virus in vitro. Molecules. 2015;20(3):5137–5151. Core-Own A™ Herbal Adaptogenic Enhancer Urtica dioica Folium The common “stinging nettle,” used medicinally, is a natural antihistamine.

Flores-Ocelotl MR, Rosas-Murrieta NH, Moreno DA, et al. Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitro. BMC Complement Altern Med. 2018;18(1):95.

Kumaki Y, Wandersee MK, Smith AJ, et al. Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin. Antiviral Res. 2011;90(1):22–32.

Uncini Manganelli RE, Zaccaro L, Tomei PE. Antiviral activity in vitro of Urtica dioica L., Parietaria diffusa M. et K. and Sambucus nigra L. J Ethnopharmacol. 2005;98(3):323–327. Core-Own A™ Herbal Adaptogenic Enhancer Hypericum perforatum Folium St. John’s wort is a neurorestorative, mood elevator, and photosensitizer.

Chen H, Muhammad I, Zhang Y, et al. Antiviral Activity Against Infectious Bronchitis Virus and Bioactive Components of Hypericum perforatum L. Front Pharmacol. 2019;10:1272.

Li YY, Bei Y, Zhang H, Li JA, Zhao W, Xiao QX, Zhang MJ, Huang YD, Xiang Q. [Study on effect of Hypericum perforatum on pharmacokinetics of zedoary turmeric oil in compound antiviral preparation]. Zhongguo Zhong Yao Za Zhi. 2013 Apr;38(7):1083-6.

Xiuying P, Jianping L, Ruofeng S, Liye Z, Xuehong W, Yan L. Therapeutic efficacy of Hypericum perforatum L. extract for mice infected with an influenza A virus. Can J Physiol Pharmacol. 2012;90(2):123–130.
Core-Own A™ Herbal Adaptogenic Enhancer Olea europaea Folium The mysterious olive leaf reflects light from its upper side, absorbs light to its underside.

Altındiş M, Aslan FG, Uzuner H, et al. Zeytin Yaprağı Ekstresi ve Propolisin Herpes Simpleks Virüsü Tip 1 Üzerine Antiviral Etkisinin Asiklovir ile Karşılaştırılması [Comparison of Antiviral Effect of Olive Leaf Extract and Propolis with Acyclovir on Herpes Simplex Virus Type 1]. Mikrobiyol Bul. 2020;54(1):79–94.

Lee-Huang S, Zhang L, Huang PL, Chang YT, Huang PL. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem Biophys Res Commun. 2003;307(4):1029–1037.

Leila A, Lamjed B, Roudaina B, et al. Isolation of an antiviral compound from Tunisian olive twig cultivars. Microb Pathog. 2019;128:245–249.

Somerville V, Moore R, Braakhuis A. The Effect of Olive Leaf Extract on Upper Respiratory Illness in High School Athletes: A Randomised Control Trial. Nutrients. 2019;11(2):358. Core-Own A™ Herbal Adaptogenic Enhancer Schisandra chinensis Fructus Wu wei zi, “five flavor fruit,” is a tangy classical Chinese medicinal tonic.

Ma WH, Lu Y, Huang H, Zhou P, Chen DF. Schisanwilsonins A-G and related anti-HBV lignans from the fruits of Schisandra wilsoniana. Bioorg Med Chem Lett. 2009;19(17):4958–4962.

Qian XJ, Zhang XL, Zhao P, et al. A Schisandra-Derived Compound Schizandronic Acid Inhibits Entry of Pan-HCV Genotypes into Human Hepatocytes. Sci Rep. 2016;6:27268. Published 2016 Jun 2.

Xu L, Grandi N, Del Vecchio C, et al. From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors. J Microbiol. 2015;53(4):288–293.

Xue Y, Li X, Du X, et al. Isolation and anti-hepatitis B virus activity of dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis. Phytochemistry. 2015;116:253–261. Core-Own A™ Herbal Adaptogenic Enhancer Musa acuminata Fructus Pericarp Botanically banana is a berry containing antiviral lectins, i.e., sugar-binding proteins.

Akkouh O, Ng TB, Singh SS, et al. Lectins with anti-HIV activity: a review. Molecules. 2015;20(1):648–668. Published 2015 Jan 6. doi:10.3390/molecules20010648

Hopper JTS, Ambrose S, Grant OC, et al. The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans. Structure. 2017;25(5):773–782.e5.

Meagher JL, Winter HC, Ezell P, Goldstein IJ, Stuckey JA. Crystal structure of banana lectin reveals a novel second sugar binding site. Glycobiology. 2005;15(10):1033–1042.

Sethiya NK, Shekh MR, Singh PK. Wild banana [Ensete superbum (Roxb.) Cheesman.]: Ethnomedicinal, phytochemical and pharmacological overview. J Ethnopharmacol. 2019;233:218–233.

Stojanović MM, Zivković IP, Petrusić VZ, et al. In vitro stimulation of Balb/c and C57 BL/6 splenocytes by a recombinantly produced banana lectin isoform results in both a proliferation of T cells and an increased secretion of interferon-gamma. Int Immunopharmacol. 2010;10(1):120–129.

Swanson MD, Winter HC, Goldstein IJ, Markovitz DM. A lectin isolated from bananas is a potent inhibitor of HIV replication. J Biol Chem. 2010;285(12):8646–8655. Core-Own A™ Herbal Adaptogenic Enhancer Oldenlandia diffusa (Hedyotis) Folium Bai Hua She She Cao, the anticancer “snake tongue flower,” contains novel cyclotides. .

Daly NL, Clark RJ, Plan MR, Craik DJ. Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochem J. 2006;393(Pt 3):619–626.

Henriques ST, Huang YH, Rosengren KJ, et al. Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. J Biol Chem. 2011;286(27):24231–24241.

Ireland DC, Wang CK, Wilson JA, Gustafson KR, Craik DJ. Cyclotides as natural anti-HIV agents. Biopolymers. 2008;90(1):51–60. doi:10.1002/bip.20886

Rosengren KJ, Daly NL, Harvey PJ, Craik DJ. The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions [published correction appears in Biopolymers. 2014 Jan;102(1):136]. Biopolymers. 2013;100(5):453–460. Core-Own A™ Herbal Adaptogenic Enhancer Eriobotrya japonica Folium The leaves of the loquat are used in medicine, but the fruits are enjoyed by all.

Cha DS, Eun JS, Jeon H. Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica. J Ethnopharmacol. 2011;134(2):305–312.

De Tommasi N, De Simone F, Pizza C, et al. Constituents of Eriobotrya japonica. A study of their antiviral properties. J Nat Prod. 1992;55(8):1067–1073.

Kim OK, Nam DE, Jun W, Lee J. Effects of Standardized Eriobotrya japonica Extract in LP-BM5 Murine Leukemia Viruses-Induced Murine Immunodeficiency Syndrome. Immunol Invest. 2016;45(2):148–160.

Matalka KZ, Abdulridha NA, Badr MM, Mansoor K, Qinna NA, Qadan F. Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway. Molecules. 2016;21(6):722.

Seong NW, Seo HS, Kim JH, et al. A 13-week subchronic toxicity study of an Eriobotrya japonica leaf extract in rats. J Ethnopharmacol. 2018;226:1–10. Core-Own A™ Herbal Adaptogenic Enhancer Tripterygium wilfordii Radix Lei gong teng, “thunder god vine,” augments therapeutic synergies in miniscule doses.

Hu W, Fu W, Wei X, Yang Y, Lu C, Liu Z. A Network Pharmacology Study on the Active Ingredients and Potential Targets of Tripterygium wilfordii Hook for Treatment of Rheumatoid Arthritis. Evid Based Complement Alternat Med. 2019;2019:5276865.

Li T, Xie J, Li Y, et al. Tripterygium wilfordii Hook F extract in cART-treated HIV patients with poor immune response: a pilot study to assess its immunomodulatory effects and safety. HIV Clin Trials. 2015;16(2):49–56.

Lin KX, Wang CZ, Qian GS.. [Effect of Tripterygium Wilfordii on Th1, Th2 Cytokines Production in Asthma Patients]. Zhongguo Zhong Xi Yi Jie He Za Zhi,21 (1), 22-4, 2001.

Rao Y, Wei HZ, Chen YF, et al. [Advances in Studies Compatibility Applied To attenuation and Synergy of Tripterygium Wilfordii]. Zhongguo Zhong Yao Za Zhi. 2008;33(14):1658–1661.

Ryu YB, Park SJ, Kim YM, et al. SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii. Bioorg Med Chem Lett. 2010;20(6):1873–1876. doi:10.1016/j.bmcl.2010.01.152

Yu JS, Tseng CK, Lin CK, et al. Celastrol inhibits dengue virus replication via up-regulating type I interferon and downstream interferon-stimulated responses. Antiviral Res. 2017;137:49–57.
Core-Own A™ Herbal Adaptogenic Enhancer Commiphora myrrha Resina The myrrh trees of the Bible exude antiseptic healing gum from their bark.

Bakari GG, Max RA, Mdegela RH, Phiri EC, Mtambo MM. Antiviral activity of crude extracts from Commiphora swynnertonii against Newcastle disease virus in ovo. Trop Anim Health Prod. 2012;44(7):1389–1393.

Bouslama L, Kouidhi B, Alqurashi YM, Chaieb K, Papetti A. Virucidal Effect of Guggulsterone Isolated from Commiphora gileadensis. Planta Med. 2019;85(16):1225–1232.

Ljaljević Grbić M, Unković N, Dimkić I, et al. Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?. J Ethnopharmacol. 2018;219:1–14. Core-Own A™ Herbal Adaptogenic Enhancer Glycyrrhiza glabra Radix Licorice root adds sweetness to any herbal formula and improves its absorption.

Baltina LA, Kondratenko RM, Baltina LA Jr, Plyasunova OA, Pokrovskii AG, Tolstikov GA. Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review). Pharm Chem J. 2009;43(10):539–548.

Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Lancet. 2003;361(9374):2045–2046.

Fiore C, Eisenhut M, Krausse R, et al. Antiviral effects of Glycyrrhiza species. Phytother Res. 2008;22(2):141–148. Core-Own A™ Herbal Adaptogenic Enhancer Curcuma longa Rhizoma Turmeric, a cousin of ginger and and stalwart of curry, is a photosensitizer.


Dong JY, Ma XY, Cai XQ, et al. Sesquiterpenoids from Curcuma wenyujin with anti-influenza viral activities. Phytochemistry. 2013;85:122–128.

He W, Zhai X, Su J, Ye R, Zheng Y, Su S. Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro. Pathogens. 2019;8(4):258.

Huang YD, Xiang Q, Yao CS, Zhang FX, Zhang H, Li XK. [Study on the preparation of zedoary turmeric oil spray and its anti-virus effects]. Zhong Yao Cai. 2007;30(3):342–345.

Liao Q, Qian Z, Liu R, An L, Chen X. Germacrone inhibits early stages of influenza virus infection. Antiviral Res. 2013;100(3):578–588.

Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864. Core-Own A™ Herbal Adaptogenic Enhancer Angelica sinensis Radix Dong quai, is a key yin tonic, containing medicinal “sulfated polysaccharides.”

Alleva LM, Cai C, Clark IA. Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza. Evid Based Complement Alternat Med. 2010;7(4):501–510.

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